BIOME DEFENSE® is the most comprehensive and advanced bladder support formula option that NAN offers.  BIOME DEFENSE® supports the mitigation or lessening of chronic bladder and pelvic pain including LUTS. 
 
This formula also supports a decrease in neurological pain, anatomical discomfort, and other pains and stresses that may be caused by uropathogenic (e.coli) bacteria.
 
BIOME DEFENSE® is an excellent choice for individuals who have extreme cases of bladder and pelvic pain or whom haven't gained satisfactory benefit from NAN entry-level bladder formulas.
 
BIOME DEFENSE® is proudly made in the USA.