BIOME DEFENSE® is the most comprehensive and advanced bladder support option that NAN produces. BIOME DEFENSE® is a suggested as a third-line approach to support the mitigation or lessening of chronic bladder and pelvic pain, lower urinary tract symptoms including the easing of nocturia.
 
This highly specialized formula contains mechanisms of action that support the calming of the central nervous system, supporting a strong response to lessening of neurological and pelvic pain, decreasing mast cells and whole-body inflammation while supporting a strong boost to the over-all immune system. 
 
BIOME DEFENSE® is an excellent option for individuals who have more complex cases of bladder and pelvic pain or whom have not gained satisfactory benefit from NAN first-line bladder entry-level formulas.