Protect yourself from Painful UTIs
Protect yourself from Painful UTIs


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Disclaimer:
Everybody is unique, and so is the IC affecting them. What works for one doesn’t always work for another. All formulas are viable and are current solutions for different individuals. Just because a formula has more bioactive ingredients doesn't mean it is the best for the individual. Below is example an example template of how to decide which product could be right for you. Browse every product by clicking on it, and to help you find a nutraceutical that helps you the most. It is okay to start with a product that isn't Bladder Rest if you want to start with a supplement with more mechanisms of actions.
Disclaimer:
Everybody is unique, and so is the IC affecting them. What works for one doesn’t always work for another. All formulas are viable and are current solutions for different individuals. Just because a formula has more bioactive ingredients doesn't mean it is the best for the individual. Below is example an example template of how to decide which product could be right for you. Browse every product by clicking on it, and to help you find a nutraceutical that helps you the most. It is okay to start with a product that isn't Bladder Rest if you want to start with a supplement with more mechanisms of actions.
Disclaimer:
Everybody is unique, and so is the IC affecting them. What works for one doesn’t always work for another. All formulas are viable and are current solutions for different individuals. Just because a formula has more bioactive ingredients doesn't mean it is the best for the individual. Below is example an example template of how to decide which product could be right for you. Browse every product by clicking on it, and to help you find a nutraceutical that helps you the most. It is okay to start with a product that isn't Bladder Rest if you want to start with a supplement with more mechanisms of actions.


Recurrent UTIs | Future UTIs | UTIs from Intercourse


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NATURAL APPROACH UROLOGY™
NATURALLY FORMULATED NUTRACEUTICALS
FOR SUPPORT OF UROGENITAL & DIGESTIVE SYNDROMES
NATURALLY FORMULATED NUTRACEUTICALS
FOR SUPPORT OF UROGENITAL & DIGESTIVE SYNDROMES
The IC Flare Cycle

Flares are Real and Not in Your Head
IC/BPS patients often struggle with “IC flares,” a sudden or dramatic worsening of their bladder symptoms. Flares can last from hours to months. IC flares can be unpredictable, disruptive, and challenging for newly diagnosed and veteran IC patients.
IC flares can be specifically triggered or sporadically appear in many ways that can irritate the bladder wall, tighten pelvic floor muscles, and sensitize nerves.
It’s still not entirely known what causes most cases of IC. But several factors have been identified that seem to contribute to the development of the condition.
These factors include:
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Any health condition or event that damages the bladder or bladder lining. For example, “bladder trauma” may be caused by bladder infections, pelvic infections, or pelvic surgery.
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Bladder overdistention caused by holding urination in for long periods of time.
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Pelvic floor muscle dysfunction.
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Autoimmune disorders.
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Pelvic inflammatory disease can be linked to bacterial infections, including sexually transmitted infections like chlamydia.
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Primary neurogenic inflammation (hypersensitivity or inflammation of pelvic nerves)
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Spinal cord trauma.
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Biofilms (Hypothesis - not enough research).
IC is an inflammatory condition of the bladder that experts believe is caused by the dysfunction of protein membranes found in the bladder lining. There's evidence that damage to the bladder wall can allow particles in the urine, such as potassium, to leak into the bladder lining, causing an inflammatory response. Usually, the bladder's lining should be able to repair itself, but this process doesn't seem to happen in people with IC.
Some studies suggest that proteins, which include the sub-type called antiproliferative factor (APF), may interfere with the regular activity of bladder cells, causing ongoing damage and irritation. The immune system may start to attack the bladder (an autoimmune response), and nerve signaling in the bladder may also become impaired. When someone with IC's bladder fills up with urine after being filtered by the kidneys, the stretching sensation causes lots of pressure and discomfort that can sometimes be intolerable.
Based on its postulated underlying causes, is interstitial cystitis a disease or a manifestation of symptoms based on various etiologies? Most likely, IC results from many uncomfortable symptoms derived from various etiologies (origins).
The two commonly most recognized subtypes of IC are:
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Non-ulcerative IC
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Ulcerative IC
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Non-ulcerative interstitial cystitis accounts for the vast majority, about 90 percent, of all IC cases. People with this type of IC develop inflammation and hemorrhages in the bladder wall, contributing to pain.
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Ulcerative interstitial cystitis is much less common, accounting for about 5 percent to 10 percent of all IC cases. People with this type of IC may develop ulcers or patches on their bladder walls.
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Another rare but severe type of IC is called end-stage interstitial cystitis. This type accounts for approximately 5 percent of all IC cases. Diagnoses are when a patient has chronic and severe IC symptoms that last more than two years. End-stage IC causes the bladder to harden, develop ulcers and become very painful.
Negative Shift in Body's Microbiome
Initial Injury to Bladder Wall
Hypersensitized Pelvic Muscles
Pain, Urgency, Frequency, Noctura
Increased Cortisol Pro-Inflammatory
Phase 1: Inflammatory Cycle
Stress, Anxiety, Acute Depression
Hypersensitized Pelvic Nerves / Tissues
Recurring Bladder Pain & Aches
Phase 2: Pain Cycle
Lower Back Pain
Food Sensitivities / Mast Cell
Pain on Bladder Fill / Suprapubic
Migratrory Pelvic Pain
Pain from Intercourse
Feeling of Loneliness / Sadness
Phase 3: Established IC / BPS
Symptoms Unique in Every Patient
Recurring Flares / Cyclical Signature
Types of Flares:
Pain BEFORE urination (that gets worse as you bladder FILLS with urine and feels better once you have emptied your bladder) points to your bladder wall.
Pain AFTER urination points to your pelvic floor as the probable source of your flare.
If pain is intense before and after urination, you may have a combination flare that is involving the bladder, muscles and nerves.
NAN Goals from 0-3 Weeks of NAN Supplementation
Flare Intensity
Most flares that the patient usually are severe.
Flare Frequency
Flares can occur every day to every couple of days.
Flare to Non-Flared Ratio
Patient usually is in a perpetual flared state.

NAN Goals from 3-10 Weeks of NAN Supplementation
Flare Intensity
Flares move from severe to moderate.
Flare Frequency
Flares moves from daily to every few days.
Flare to Non-Flared Ratio
Patient has less flares and intensity.

NAN Goals from 10-26 Weeks of NAN Supplementation
Flare Intensity
Flares become less often, quality of life improvement.
Flare Frequency
Less than three times per month or none at all.
Flare to Non-Flared Ratio
Patient may reach positive degrees of homeostasis.
